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Cyclic adenosine monophosphate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenylate Cyclase (1) Antibiotic (4) Bacterial (3) Biochemical Assay Reagents (1) Calcium Channel (3) CRFR (1) Endogenous Metabolite (1) Isotope-Labeled Compounds (3) Nucleoside Antimetabolite/Analog (1) Phosphodiesterase (PDE) (5) STING (2)
By Research Areas:	Cancer (6) Cardiovascular Disease (4) Infection (4) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (4)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Adenosine Kinase Adenosine Receptor Adenosine Deaminase Cyclic GMP-AMP Synthase HCN Channel

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1511

Cyclic AMP 5+ Cited Publications Cyclic adenosine monophosphate; adenosine Cyclic 3', 5'-monophosphate; cAMP	Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .

HY-B1511A

Cyclic AMP sodium 5+ Cited Publications Cyclic adenosine monophosphate sodium; adenosine Cyclic 3', 5'-monophosphate sodium; cAMP sodium; Cyclic AMP sodium	Biochemical Assay Reagents	Neurological Disease Metabolic Disease Cancer
Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes .

HY-W587488

Adenosine 3′-monophosphate

3′-AMP
Nucleoside Antimetabolite/Analog Cancer

Adenosine 3′-monophosphate (3′-AMP), a nucleotide, is a cyclic AMP production agonist .

Adenosine 3′-monophosphate 3′-AMP	Nucleoside Antimetabolite/Analog	Cancer
Adenosine 3′-monophosphate (3′-AMP), a nucleotide, is a cyclic AMP production agonist .

HY-B1511S

Cyclic AMP-13C5 Cyclic adenosine monophosphate-sup>13C₅; adenosine Cyclic 3', 5'-monophosphate-sup>13C₅; cAMP-sup>13C₅	Isotope-Labeled Compounds	Others
Cyclic AMP- ¹³C₅ is a deuterated cyclic AMP.

HY-14132

BMS-665053	CRFR	Neurological Disease
BMS-665053 is a corticotropin-releasing factor-1 (CRF1) receptor antagonist (IC₅₀ = 1.0 nM). BMS-665053)11 is a potent inhibitor of CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells (IC₅₀ = 4.9 nM) .

HY-N0113

Hordenine 1 Publications Verification Ordenina; Peyocactine	Bacterial Antibiotic	Infection Cardiovascular Disease
Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-N0113B

Hordenine hydrochloride Ordenina hydrochloride; Peyocactine hydrochloride	Antibiotic	Infection
Hordenine (hydrochloride), an alkaloid found in?plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-108974

Drotaverine hydrochloride	Phosphodiesterase (PDE) Calcium Channel
Drotaverine (hydrochloride) is a type *4 cyclic* nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC)** blocker, blocks the degradation of 3',5'-cyclic adenosine monophosphate. Drotaverine (hydrochloride) exhibits in vivo antispasmodic efficacy without anticholinergic effects.

HY-N0113R

Hordenine (Standard) Ordenina (Standard); Peyocactine (Standard)	Bacterial Antibiotic	Infection Cardiovascular Disease
Hordenine (Standard) is the analytical standard of Hordenine. This product is intended for research and analytical applications. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-P2867

Phosphodiesterase II, Bovine Spleen 3′-Exonuclease	Phosphodiesterase (PDE)	Neurological Disease
Phosphodiesterase II (EC 3.1.16.1), namely phosphodiesterase 2, is mainly involved in the hydrolysis of the important second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), and is often used in biochemical research. Phosphodiesterase II is expressed in a variety of tissues, such as the adrenal medulla, brain, heart, platelets, macrophages and endothelial cells, and is involved in the regulation of many different intracellular processes .

HY-N0113S

Hordenine-d6 Ordenina-d₆; Peyocactine-d₆	Isotope-Labeled Compounds Bacterial Antibiotic	Infection Cardiovascular Disease
Hordenine-d6 (Ordenina-d6) is the deuterium labeled Hordenine. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-108974S

Drotaverine-d10 hydrochloride	Isotope-Labeled Compounds Phosphodiesterase (PDE) Calcium Channel
Drotaverine-d₁₀ (hydrochloride) is the deuterium labeled Drotaverine hydrochloride. Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3',5'-cyclic adenosine monophosphate. Drotaverine hydrochloride exhibits in vivo antispasmodic efficacy without anticholinergic effects[1][2].

HY-B1294

Amrinone Inamrinone
Amrinone (Inamrinone) is a positive inotropic-vasodilator agent. Amrinone is a selective phosphodiesterase III inhibitor that increases cyclic adenosine monophosphate by preventing its breakdown. Amrinone is also an orally active, non-glycosidic and non-catecholamine cardiotonic agent .

HY-131454

SR-717 Maximum Cited Publications 10 Publications Verification	STING	Inflammation/Immunology Cancer
SR-717 is a non-nucleotide STING agonist with EC₅₀s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity .

HY-131454A

SR-717 free acid	STING	Inflammation/Immunology Cancer
SR-717 free acid is a non-nucleotide STING agonist with EC₅₀s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 free acid is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity .

HY-120241

Reticulol K 251-1	Phosphodiesterase (PDE)	Cancer
Reticulol (K 251-1) is an inhibitor of cyclic adenosine 3', 5'-monophosphate phosphodiesterase. Reticulol shows antitumor activity independent with cell cycle arrest or apoptosis. Reticulol inhibits cell growth of murine melanoma cells and human lung tumor cells. Reticulol protects its lung metastasis via the bloodstream by inhibiting the growth of B16F10 melanoma .

HY-147946

PDE1-IN-4	Phosphodiesterase (PDE) Calcium Channel	Inflammation/Immunology
PDE1-IN-4 (compound 2g) is a potent and selective PDE1 (phosphodiesterase-1) inhibitor, with IC₅₀ values of 10, 145, and 354 nM for PDE1C, PDE1A, and PDE1B, respectively. PDE1-IN-4 inhibits myofibroblast differentiation of human lung fibroblasts induced by TGF-β1. PDE1-IN-4 shows anti-fibrosis effects through the regulation of cAMP (3′,5′-cyclic adenosine monophosphate) and cGMP (3′,5′-cyclic guanosine monophosphate). PDE1-IN-4 can be used for idiopathic pulmonary fibrosis (IPF) research .

HY-N2168

Pinoresinol 4-O-β-D-glucopyranoside (+)-Pinoresinol 4-O-β-D-glucopyranoside	Others	Cardiovascular Disease
Pinoresinol 4-O-β-D-glucopyranoside ((+)-Pinoresinol 4-O-β-D-glucopyranoside) is the major active furofuran type lignans in Fructus Forsythiae. Pinoresinol 4-O-β-D-glucopyranoside shows antioxidant, blood pressure reducing, and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory effects .

HY-146356

Adenylyl cyclase type 2 agonist-1	Adenylate Cyclase	Inflammation/Immunology
Adenylyl cyclase type 2 agonist-1 (Compound 73) is a potent agonist of adenylyl cyclase type 2 (AC2) with the EC₅₀ of 90 nM. Adenylyl cyclase type 2 agonist-1 inhibits expression of Interleukin-6, making it a potential lead compound against respiratory diseases .

Cyclic AMP sodium 5+ Cited Publications Cyclic adenosine monophosphate sodium; adenosine Cyclic 3', 5'-monophosphate sodium; cAMP sodium; Cyclic AMP sodium	Biochemical Assay Reagents
Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes .

(Trp4)-Kemptide	Peptides	Others
(Trp4)-Kemptide is a peptide substrate for adenosine 3',5'-cyclic monophosphate-dependent protein kinase .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1511

Cyclic AMP Maximum Cited Publications 6 Publications Verification Cyclic adenosine monophosphate; adenosine Cyclic 3', 5'-monophosphate; cAMP	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .

HY-N0113

Hordenine 1 Publications Verification Ordenina; Peyocactine	Cardiovascular Disease Alkaloids Structural Classification Monophenols other families Classification of Application Fields Other Alkaloids Source classification Phenols Plants Disease Research Fields	Bacterial Antibiotic
Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-N0113B

Hordenine hydrochloride Ordenina hydrochloride; Peyocactine hydrochloride	Coryphantha vivipara var arizonica Structural Classification Alkaloids Monophenols Cactaceae Other Alkaloids Source classification Phenols Plants	Antibiotic
Hordenine (hydrochloride), an alkaloid found in?plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-N0113R

Hordenine (Standard) Ordenina (Standard); Peyocactine (Standard)	Cardiovascular Disease Structural Classification Alkaloids other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields	Bacterial Antibiotic
Hordenine (Standard) is the analytical standard of Hordenine. This product is intended for research and analytical applications. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-120241

Reticulol K 251-1	Structural Classification Microorganisms Source classification Phenols Polyphenols	Phosphodiesterase (PDE)
Reticulol (K 251-1) is an inhibitor of cyclic adenosine 3', 5'-monophosphate phosphodiesterase. Reticulol shows antitumor activity independent with cell cycle arrest or apoptosis. Reticulol inhibits cell growth of murine melanoma cells and human lung tumor cells. Reticulol protects its lung metastasis via the bloodstream by inhibiting the growth of B16F10 melanoma .

HY-N2168

Pinoresinol 4-O-β-D-glucopyranoside (+)-Pinoresinol 4-O-β-D-glucopyranoside	Cardiovascular Disease Monophenols other families Classification of Application Fields Source classification Lignans Phenols Phenylpropanoids Plants Disease Research Fields	Others
Pinoresinol 4-O-β-D-glucopyranoside ((+)-Pinoresinol 4-O-β-D-glucopyranoside) is the major active furofuran type lignans in Fructus Forsythiae. Pinoresinol 4-O-β-D-glucopyranoside shows antioxidant, blood pressure reducing, and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory effects .

Cat. No.	Product Name	Chemical Structure

HY-N0113S

Hordenine-d6
Hordenine-d6 (Ordenina-d6) is the deuterium labeled Hordenine. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .

HY-B1511S

Cyclic AMP-13C5

Cyclic AMP- ¹³C₅ is a deuterated cyclic AMP.

Cyclic AMP-13C5
Cyclic AMP- ¹³C₅ is a deuterated cyclic AMP.

HY-108974S

Drotaverine-d10 hydrochloride
Drotaverine-d₁₀ (hydrochloride) is the deuterium labeled Drotaverine hydrochloride. Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3',5'-cyclic adenosine monophosphate. Drotaverine hydrochloride exhibits in vivo antispasmodic efficacy without anticholinergic effects[1][2].

Drotaverine-d10 hydrochloride

Drotaverine-d₁₀ (hydrochloride) is the deuterium labeled Drotaverine hydrochloride. Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3',5'-cyclic adenosine monophosphate. Drotaverine hydrochloride exhibits in vivo antispasmodic efficacy without anticholinergic effects[1][2].

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Cyclic adenosine monophosphate

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products